Realistically, yes. Actually I'm not sure what age she is in the show, but if I had to guess, I'd say no younger than mid 30's, which would put her in her mid to late 40's in this picture. Some women DO manage to look pretty good at that age.
Since this was an art trade with I decided to use her influence in this. She does a lot of cool Edna art, sometimes with teenage Bart.